How is bullous lupus treated?
Dapsone is the initial treatment of choice for bullous systemic lupus erythematosus. The response is usually dramatic, with cessation of new blister formation within 1-2 days and rapid healing of existing lesions. Low doses (25-50 mg/d) are often effective, although a higher dosage is sometimes required.
What is the long term prognosis of someone with lupus?
The prognosis of lupus is better today than ever before. With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease.
What are the final stages of lupus?
According to the Lupus Research Alliance, about half of all people with lupus experience cognitive difficulties with thought processes. Around 1 in 5 people experience headaches, memory loss, mood swings, and stroke. Blood clots might also develop. These might also lead to dangerous complications, such as stroke.
What causes bullous systemic lupus erythematosus?
Bullous systemic lupus erythematosus (BSLE) is a rare cutaneous complication of systemic lupus erythematosus (SLE). It is a heterogeneous disease that is caused by autoantibodies to the dermoepidermal junction, mainly type VII collagen.
What is bullous lupus erythematosus?
Bullous systemic lupus erythematosus (SLE) is an autoimmune subepidermal blistering disease that occurs in patients with SLE. It can be associated with antibodies against type VII collagen. Bullous SLE is also called bullous eruption of SLE and vesiculobullous SLE.
How does lupus affect the kidneys?
Lupus nephritis occurs when lupus autoantibodies affect structures in your kidneys that filter out waste. This causes kidney inflammation and may lead to blood in the urine, protein in the urine, high blood pressure, impaired kidney function or even kidney failure.
What is the most serious form of lupus?
There are several different types of lupus: Systemic lupus erythematosus (SLE) is the most common and most serious type of lupus. SLE affects all parts of the body.
How do you know if lupus is affecting your kidneys?
Foamy urine (due to excess protein in urine) High blood pressure. Swelling in your hands, ankles or feet. High levels of a waste product called creatinine in your blood.
What does lupus do to the kidneys?
Lupus can cause a kidney disease called lupus nephritis. Lupus nephritis is inflammation in the kidneys that can make them stop working. When the kidneys aren’t working well, waste builds up in the blood and extra water builds up in the body. Lupus nephritis is most common in people ages 20 to 40.
What is bullous eruption?
The term bullous drug eruptions refers to adverse drug reactions that result in fluid-filled blisters or bullae. Blistering can be due to various medications, prescribed or over-the-counter, natural or synthetic. Blistering may be localised and mild, or widespread and severe, even life-threatening.
What triggers Bullous pemphigoid?
Causes of bullous pemphigoid Bullous pemphigoid is caused by a problem with the immune system (the body’s defence against infection). Instead of attacking germs, it attacks and damages the skin. It’s not known why this happens. Sometimes it’s been linked to skin damage (such as sunburn) or taking certain medicines.