How do you give SMOFlipid?
The recommended dosage of SMOFlipid for adult patients is 1 to 2 g/kg/day and should not exceed 2.5 g/kg/day. The initial rate of infusion should be 0.1 g/minute for the first 15 to 30 minutes of infusion. If tolerated, gradually increase until reaching the required rate after 30 minutes.
What SMOFlipid 20?
SMOFlipid 20% (6% soybean oil / 6% medium chain triglycerides / 5% olive oil/ 3% fish oil) is indicated for supply of energy and essential fatty acids and omega-3 fatty acids to adult patients, as part of a parenteral nutrition regimen, when oral or enteral nutrition is impossible, insufficient or contra-indicated.
How do you calculate TPN fat?
Lipids : start at 0.5-1.0 g/kg/d; divide g/d by 0.2 ( or multiply by 5) to obtain volume of 20% lipid emulsion needed (in milliliters or cc). 20% lipid emulsion has 2 kcal/cc and 10 kcal/gram of lipid.
What is the difference between SMOFlipid and intralipid?
Given the various oils in Smoflipid, the primary concern with dispensing this product instead of Intralipid is with patients who have an allergy to fish (which poses no problem with Intralipid). Also, unlike Intralipid, Smoflipid does not have a pediatric indication if dispensed in error to this population.
When do we use SMOFlipid?
INDICATIONS AND USAGE SMOFlipid is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition (PN) when oral or enteral nutrition is not possible, insufficient, or contraindicated.
What does SMOF stand for lipids?
SMOF Lipid for Children With Parenteral Nutrition Induced Liver Injury (SMOF)
| Study Type : | Expanded Access |
| Official Title: | Compassionate Use of an Intravenous Fat Emulsion Comprised of Soy Oil, Medium Chain Triglycerides, Olive Oil, and Fish Oil for Children With Parenteral Nutrition Induced Liver Injury |
What is in TPN formula?
TPN is a mixture of separate components which contain lipid emulsions, dextrose, amino acids, vitamins, electrolytes, minerals, and trace elements. [7][8] TPN composition should be adjusted to fulfill individual patients’ needs. The main three macronutrients are lipids emulsions, proteins, and dextrose.
How do you calculate TPN osmolality?
To calculate solution osmolarity:
- multiply grams of dextrose per liter by 5.
- multiply grams of protein per liter by 10.
- add a & b.
- add 300 to 400 to the answer from “c”. (Vitamins and minerals contribute about 300 to 400 mOsm/L.)
What is Smoflipid?
SMOFlipid is a composite parenteral nutrition (PN) lipid, comprised of soybean oil (30%), medium-chain triglycerides (MTCs, 30%), olive oil (25%), and fish oil (15%).
Is SMOFlipid a TPN?
Total parenteral nutrition (TPN) is usually prescribed for patients recommended prolonged fasting after LT. The supplement of SMOFlipid (soybean oil, MCT oil, olive oil, and fish oil) has the advantage of being easily metabolised to produce energy, and it has anti-inflammatory effects.
Is SMOFlipid FDA approved?
The company received FDA approval for Smoflipid in July 2016. Smoflipid is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.
What is the dosage of smoflipid for adults?
Adult Dosing Information. The recommended dosage of Smoflipid for adult patients is 1 to 2 grams/kg per day and should not exceed 2.5 grams/kg per day. 1 The initial rate of infusion should be 0.5 mL/min for the first 15 to 30 minutes of infusion. If tolerated, gradually increase until reaching the required rate after 30 minutes.
What is the lipid content of smoflipid?
The lipid content of Smoflipid is 0.20 g/mL, and comprises a mixture of soybean oil, medium-chain triglycerides (MCTs), olive oil, and fish oil. The mean essential fatty acid content of Smoflipid is 35 mg/mL (range of 28 to 50 mg/mL) linoleic acid (omega-6) and 4.5 mg/mL (range of 3 to 7 mg/mL) α-linolenic acid (omega-3).
What is smoflipid and what are its side effects?
Smoflipid ( lipid injectable emulsion) is used as a source of calories and fatty acids in adults who are critically or chronically ill. What Are Side Effects of Smoflipid? Common side effects of Smoflipid may include: Deaths in preterm infants after infusion of intravenous lipid emulsions have been reported in the medical literature.
What is the generic name for smoflipid?
Smoflipid Dosage. Generic name: SOYBEAN OIL 6g in 100mL, MEDIUM-CHAIN TRIGLYCERIDES 6g in 100mL, OLIVE OIL 5g in 100mL, FISH OIL 3g in 100mL. Dosage form: injection, emulsion. Medically reviewed on August 23, 2018.