How do you find the triangulation of a number?
To explain this, they developed the concept of a “triangulation number,” which represents the number of unique environments that subunits occupy. You can find the allowable triangulation numbers by tracing out equilateral triangles on this hexagonal net of subunits.
What does triangulation number mean?
The triangulation number (T) indicates the number of structural units per face of the icosahedron. In a T = 1 virus, one structural unit (composed of three different protein subunits: gray, red, and blue) create the icosahedron face. (B) Virion capsids with T = 1, T = 3, and T = 4.
How many amino acids are there in a capsomere of TMV?
Each capsomere contains 158 amino acids. TMV viruses are those viruses that cause mosaic disease in tobacco.
What is the T number virology?
The capsid is composed 60 asymmetric units made of 7 proteins (T=7), for a total of 420 capsid proteins. These capsids are skewed, and are therefore described as either right- (dextro) or left- (laevo) handed.
What are icosahedral viruses?
Icosahedral. These viruses appear spherical in shape, but a closer look actually reveals they are icosahedral. The icosahedron is made up of equilateral triangles fused together in a spherical shape. This is the most optimal way of forming a closed shell using identical protein sub-units.
What do you mean by Capsomere?
The capsomere is a subunit of the capsid, an outer covering of protein that protects the genetic material of a virus. Capsomeres self-assemble to form the capsid.
What is the size of a flu virus?
Influenza A virus belongs to the Orthomyxoviridae family, and produces virions of around 80–120 nm in diameter that contain an RNA genome of approximately 13.5 kb in size.
What is the size of the smallest virus?
AAV is the smallest DNA virus with an average size of 20 nm. AAV was discovered in 1965 as a defective contaminating virus in an adenovirus stock (Atchison et al., 1965).
What is the total number of amino acids when the capsid of TMV contains 2130 Capsomeres?
336540
TMV has 2130 capsomeres. The protein monomer units consist of 158 amino acids which are assembled into four main alpha-helices, joined by a prominent loop proximal to the axis of the virion. Thus, the total number of the amino acid is 2130 x158 = 336540.
What is the difference between virion and viroid?
Viruses and viroids are disease-causing organisms. The difference between virion (virus) and viroid is that viroid is a smaller form of a virus with RNA nucleic acid. In contrast, a virus can have either DNA or RNA.
What is a capsomere?
The capsomere is a subunit of the capsid, an outer covering of protein that protects the genetic material of a virus. Capsomeres self-assemble to form the capsid.
What are the different types of capsomeres in viruses?
Each capsomere has several protomers self-assembled with each other. Moreover, capsomeres are arranged differently in the capsid in order to provide a shape to the viral capsid. Helical, icosahedral and complex are three types of capsomere arrangements in viruses. However, the arrangement of capsomeres is unique for a particular virus.
Which subunits aggregate to form capsomeres?
Subunits called protomers aggregate to form capsomeres. Various arrangements of capsomeres are: 1) Icosahedral, 2) Helical, and 3) Complex. 1) Icosahedral- An icosahedron is a polyhedron with 12 vertices and 20 faces.
How are capsomeres in the capsid shell joined together?
The capsomeres in the capsid shell are joined together via complexes known as intercapsomeric triplexes, which contain two copies of one protein and one copy of another.