What are differential diagnosis of jaundice?
Gallstone formation is the most common and benign posthepatic process that causes jaundice; however, the differential diagnosis also includes serious conditions such as biliary tract infection, pancreatitis, and malignancies.
What causes hemolytic jaundice?
Hemolytic jaundice, also known as prehepatic jaundice, is a type of jaundice arising from hemolysis or excessive destruction of red blood cells, when the byproduct bilirubin is not excreted by the hepatic cells quickly enough.
What is the differential diagnosis of Anaemia with jaundice?
Anemia is reported in hereditary hemochromatosis associated with hemolytic anemia’s and congenital dyserythropoietic anemia. The presence of anemia with jaundice suggests an underlying hemolytic disorder with unconjugated hyperbilirubinemia. However, conjugated hyperbilirubinemia with anemia poses a diagnostic dilemma.
What would be manifestations of hemolytic jaundice?
Hemolytic jaundice, congenital: Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen).
What is pathological and physiological jaundice?
In most cases, it is a mild, transient, and self-limiting condition and is referred to as “physiological Jaundice.” However, it is imperative to distinguish this from a more severe form called “pathological Jaundice.” Failure to identify and treat this entity may result in bilirubin encephalopathy and associated …
What test detects hemolytic anemia?
To diagnose hemolytic anemia, your doctor will do a physical exam and order blood tests. Additional tests may include a urine test, a bone marrow test, or genetic tests.
Why does unconjugated bilirubin increase in hemolytic jaundice?
Increased bilirubin production and consequential unconjugated hyperbilirubinemia can result from increased catabolic degradation of hemoglobin and other heme proteins, typically due to accelerated hemolysis, a large hematoma, dyserythropoiesis (e.g., megaloblastic and sideroblastic anemias), or sometimes due to …
What is the difference between physiologic and Nonphysiologic jaundice?
Physiologic And Non-Physiologic Jaundice This type of jaundice occurs more than 24 hours after a baby is born. Non-physiological Jaundice occurs much sooner, with infants developing jaundice less than 24 hours after birth.