What does DRESS syndrome look like?
The classic clinical presentation of DRESS includes the triad of fever, rash, and internal organ involvement. Fever and rash are the most common clinical manifestations, occurring in 85% and 75% of cases, respectively.
Is DRESS syndrome fatal?
Because DRESS syndrome is fatal for about 10% of those who develop it, early diagnosis and treatment are essential.
What does a dress rash look like?
Drug reaction with eosinophilia and systemic symptoms (DRESS) This is a rare type of drug rash that can be life threatening. You may not notice symptoms of DRESS for 2 to 6 weeks after starting a new drug. This type of rash looks red, often starting on the face and upper body.
Is DRESS syndrome an autoimmune disease?
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is associated with long-term autoimmune sequelae. Patients require careful monitoring for autoimmune disease following recovery from DRESS syndrome.
Can DRESS syndrome be cured?
Most patients recover completely after drug withdrawal and appropriate therapy. However, some patients with DRESS syndrome suffer from chronic complications and approximately 10% die, primarily from visceral organ compromise.
What drugs cause DRESS syndrome?
Medicines most commonly associated with DRESS syndrome are anticonvulsants, antibiotics (particularly beta-lactams), and allopurinol. Other medications that are known to be associated with DRESS include non-steroidal anti-inflammatory drugs, captopril, mood stabilisers, and antiretrovirals.
How quickly does SJS progress?
If your case of SJS is caused by a drug, symptoms appear about one to three weeks after you start taking medication. The flu-like illness (fever, cough and headache, skin pain) is followed first by a rash and then peeling.
What is the difference between dress and SJS?
For DRESS syndrome, patients had prodromal symptoms of itching, fever and facial edema. Patients with SJS commonly had prodromal symptoms of fever and malaise. The first skin lesions appeared on the extremities and face in DRESS and on the trunk in SJS (Table 2). The trunk lesions in SJS were tender.