What is the chemical name of sulfanilamide?
Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group….Sulfanilamide.
| Clinical data | |
|---|---|
| IUPAC name 4-amino benzene sulfonamide… | |
| CAS Number | 63-74-1 |
| PubChem CID | 5333 |
| DrugBank | DB00259 |
What is the chemical formula for sulfonamide?
Sulfanilamide | C6H8N2O2S – PubChem.
What is sulfonamide in chemistry?
sulfonamide, also spelled Sulphonamide, any member of a class of chemical compounds, the amides of sulfonic acids. The class includes several groups of drugs used in the treatment of bacterial infections, diabetes mellitus, edema, hypertension, and gout.
Is sulfanilamide and sulfonamide the same thing?
Sulfanilamide is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant.
What is sulfonamide used for?
Sulfonamides inhibit the growth of harmful bacteria in the body. They are used to treat a variety of infections, including urinary tract infections, skin infections, lung infections, and other bacterial and parasitic infections.
What is sulfanilamide soluble in?
The solubility of sulfanilamide is the highest in acetone and the least in toluene among the mono solvents. The order of solubility in mono solvents is toluene < ethyl acetate < 1-octanol < water < benzene < 1-butanol < 2-butanol < 2-propanol < 1-propanol < ethanol < methanol < acetone.
What is the pKa of sulfonamide?
This drug is, according to the computed pKa value (5.9), also in water solution the most acidic compound of the sulfonamides investigated. The computed pKa values varied between 5.9 and 12.6 and correlate well with the available experimental pKa’s found in the literature.
What is sulfonamide group?
Sulfonamides, or “sulfa drugs,” are a group of medicines used to treat bacterial infections. They may be prescribed to treat urinary tract infections (UTIs), bronchitis, eye infections, bacterial meningitis, pneumonia, ear infections, severe burns, traveler’s diarrhea, and other conditions.
What is the derivative of sulfonamide?
Single-target applications of sulfonamides
| Mechanism | Compound(s) | |
|---|---|---|
| Cancer | Inhibitors of CA IX carbonic anhydrase | tertiary sulfonamide derivatives of pyridyl-indole based heteroaryl chalcone |
| Inhibitors of CA II carbonic anhydrase | 2-(substituted phenyl-amino)-N-(4-sulfamo-ylphenyl) acetamide |
Which of the following is a Sulpha drug?
So, sulphapyridine and prontosil are the only sulfa drugs here.
What is an example of a sulfonamide?
Examples of sulfonamides includes sulfadiazine, sulfamethizole (brand name: Thiosulfil Forte), sulfamethoxazole (Gantanol), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin), and various high-strength combinations of three sulfonamides.