What organelles are found in Leydig cells?
Because these cells are responsible for testosterone production, they have features of steroid-secreting cells, including large and well developed smooth endoplasmic reticulum, large and numerous lipid droplets, and significant numbers of mitochondria with tubulovesicular cristae.
What is produced in the Leydig cells?
Herein we summarize important discoveries made over many years about Leydig cell function and regulation. Fetal Leydig cells produce the high levels of androgen (testosterone or androstenedione, depending upon the species) required for differentiation of male genitalia and brain masculinization.
Where do Leydig cells come from?
The Leydig cells appear embryonic gonad shortly after testis determination and probably arise from multiple embryonic tissues including the coelomic epithelium, gonadal ridge mesenchyme, and migrating mesonephric cells [6].
Which hormone is secreted by Leydig cells?
Testosterone
Testosterone. Testosterone is secreted from the interstitial cells of Leydig, which are in large concentration in the testis in newborns and adult males after puberty.
What type of cells are Leydig cells?
Leydig cells (LC) belong to the somatic cell complement of the testis and are located in the interstitial tissue, that is, the space between seminiferous tubules (Fig. 1).
What are Leydig?
Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testicle. They produce testosterone in the presence of luteinizing hormone (LH).
Are Leydig cells epithelial?
Interstitial or Leydig cells are located in the connective tissue surrounding the seminiferous tubules. They produce testosterone, the male sex hormone responsible for the growth and maintenance of the cells of the germinal epithelium and the development of secondary sex characteristics.
Do Leydig cells secrete testosterone?
Leydig cells (LC) are present in the testicular interstitial tissue, and their main function is to produce testosterone (T) for the maintenance of spermatogenesis and extratesticular androgenic and anabolic functions.
Does Leydig cells produce estrogen?
In the adult testis, estrogen is synthesized by Leydig cells and the germ cells, producing a relatively high concentration in rete testis fluid. Estrogen receptors are present in the testis, efferent ductules and epididymis of most species.
What type of tissue is Leydig cells?
testicular interstitial tissue
Leydig cells (LC) are present in the testicular interstitial tissue, and their main function is to produce testosterone (T) for the maintenance of spermatogenesis and extratesticular androgenic and anabolic functions.
Why are the Leydig cells eosinophilic?
Why are the Leydig cells eosinophilic? They contain numerous mitochondria.